We may require additional funding to continue our research and product development programs, conduct pre-clinical studies and
clinical trials, fund operating expenses, pursue regulatory approvals for our product candidates, file and prosecute patent applications and enforce or defend patent claims, if any, and fund product in-licensing and any possible acquisitions.
我们可能需要额外的资金,以继续我们的研究和产品开发计划,进行临床前研究,临床试验中,都需要操作基金的费用,这些都需要为我们的产品的候选人寻求监管部门的批准,文件和起诉的专利申请,以及执行或保护专利的权利要求,如果可能的话,还有产品基金的许可和任何可能的收购。
Investing Activities. During the years ended December 31, 2011, 2010 and 2009, we have spent $226, $2,171 and $901, respectively, on capital expenditures. These expenditures have been primarily related to leasehold improvements and the purchase of laboratory equipment for our research and development projects.
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Contractual Obligations合约责任
Our funding requirements, both for the next 12 months and beyond, will include required payments under operating leases and fixed
and contingent payments under our licensing and collaboration agreements.我们的资金需求,在未来12个月及以后,将包括在根据经营租赁支付和固定我们的授权及合作协议下的付款。
Based on assumed achievement of milestones covered under each agreement, the timing and payment of which is highly uncertain.
We periodically assess the scientific progress and merits of each of our programs to determine if continued research and development
is commercially and economically viable. Certain of our programs have been terminated due to the lack of scientific progress and prospects for ultimate commercialization. Because of the uncertainties associated with research and development in these programs, the duration and completion costs of our research and development projects are difficult to estimate and are subject to considerable variation.
Our inability to complete research and development projects in a timely manner or failure to enter into collaborative agreements could significantly increase capital requirements and adversely affect our liquidity.我们无法及时或未能订立的合作协议,在完成研究和开发项目中,可能会有增加资本的要求,这对我们的资本的流动性会产生不利影响。
Our cash requirements may vary materially from those now planned because of results of research and development and product#p#分页标题#e#
testing, changes in existing relationships or new relationships with licensees, licensors or other collaborators, changes in the focus and direction of our research and development programs, competitive and technological advances, the cost of filing, prosecuting, defending and enforcing patent claims, the regulatory approval process, manufacturing and marketing and other costs associated with the commercialization of products following receipt of regulatory approvals and other factors.
The above discussion contains forward-looking statements based on our current operating plan and the assumptions on which it relies. There could be deviations from that plan that would consume our assets earlier than planned.Off-Balance Sheet Arrangements and Guarantees
We have no obligations under off-balance sheet arrangements and do not guarantee the obligations of any other unconsolidated entity.我们没有义务保持债务平衡,不保证承担任何其他未合并实体的义务。